RP guard filter consistently guards against contamination of the analytical separation column. By eliminating even, the smallest particles, residues of iron oxide, and bacteria, it effectively guards the analytical separation column against contamination. In the HPLC system, filters such as inline filters, pre-column filters, and column guards shield analytical columns against wear and early failure. Due to the steady build-up of irreversibly bound compounds on the stationary phase and particle accumulation on the frit, the chromatographic separation of the HPLC column starts to deteriorate over time. RP guard filter has a silver-coloured robust and durable body.